| Name | VU 0409106 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4404 |
| Prices | $149.00, $629.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Modulator |
| Cas Number | 1276617-62-9 |
| Chemical Name | 3-Fluoro-N-(4-methyl-2-thiazolyl)-5-(5-pyrimidinyloxy)benzamide |
| Formula | C15H11FN4O2S |
| Molecular Weight | 330.34 |
| Purity | >98 % |
| Description | Potent and selective mGlu 5 negative allosteric modulator (IC 50 = 49 nM at human mGlu 5 ). Selective for mGlu 5 over a panel of GPCRs and ion channels. Exhibits no significant nonspecific binding in rat brain homogenates in vitro . Inhibits marble burying behavior in mice. Brain penetrant. |
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