| Name | VU 0483605 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5379 |
| Prices | $149.00, $629.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Modulator |
| Cas Number | 1623101-11-0 |
| Chemical Name | 3-Chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide |
| Formula | C20H10Cl3N3O3 |
| Molecular Weight | 446.67 |
| Purity | >98 % |
| Description | Positive allosteric modulator at mGlu 1 (EC 50 values are 356 and 390 nM for rat and human receptors, respectively). Exhibits >25-fold selectivity for mGlu 1 over mGlu 4 . Potentiates the decreased glutamate-induced calcium response in mGlu 1 mutant cell models of schizophrenia. |
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