VU 591 hydrochloride

Name VU 591 hydrochloride
Supplier Tocris Bioscience
Catalog 3891
Prices $155.00, $645.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 1315380-70-1
Chemical Name 6-Nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazolehydrochloride
Formula C16H12N6O5.HCl
Molecular Weight 404.76
Purity >99 %
Description Selective renal outer medullary potassium channel (K ir 1.1, ROMK) antagonist (IC 50 = 300 nM). Thought to block the intracellular pore of the K ir 1.1 channel. Exhibits no effect on K ir 7.1 at concentrations up to 10 μ M; does not inhibit K ir 2.1, K ir 2.3 or K ir 4.1. Displays similar potency to VU 590 (Cat. No. 3891).
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