VULM 1457

• Supplier: Tocris Bioscience
• Catalog: 2494
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 228544-65-8
• Chemical Name: N-[2,6-bis(1-Methylethyl)phenyl]-N'-[4-[(4-nitrophenyl)thio]phenyl]urea
• Formula: C25H27N3O3S
• Molecular Weight: 449.57
• Purity: >99 %
• Description: Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor. Decreases cholesterol levels in the plasma and liver of diabetic-hypercholesterolemic rats.

Product References

Protective effect of simvastatin and VULM 1457 in ischaemic-reperfused myocardium - Protective effect of simvastatin and VULM 1457 in ischaemic-reperfused myocardium

Adameova A, Kuzelova M, Faberova V, Svec P. Pharmazie. 2006 Sep;61(9):807-8.

The myocardial infarct size-limiting and antiarrhythmic effects of - The myocardial infarct size-limiting and antiarrhythmic effects of

Adameova A, Ravingerova T, Svec P, Faberova V, Kuzelova M. Eur J Pharmacol. 2007 Dec 8;576(1-3):114-21. Epub 2007 Aug 3.

Effect of VULM 1457, an ACAT inhibitor, on serum lipid levels and on real time - Effect of VULM 1457, an ACAT inhibitor, on serum lipid levels and on real time

Vojtassakova E, Synekova M, Tazka D, Matyas S, Hozova R, Sadlonova I, Svec P. Gen Physiol Biophys. 2007 Dec;26(4):254-9.