( S )-WAY 100135 dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 3933
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 149007-54-5
• Chemical Name: (S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamidedihydrochloride
• Formula: C24H33N3O2.2HCl
• Molecular Weight: 468.47
• Purity: >99 %
• Description: Potent, selective 5-HT 1A receptor antagonist (IC 50 = 15 nM). Selective over 5-HT 1B , 1C , 2 , α 1 , α 2 and D 2 receptors (IC 50 > 1000 nM). Centrally active on systemic administration.

Product References

(S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide - (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide

Cliffe IA, Brightwell CI, Fletcher A, Forster EA, Mansell HL, Reilly Y, Routledge C, White AC. J Med Chem. 1993 May 14;36(10):1509-10.

WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A - WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A

Fletcher A, Bill DJ, Bill SJ, Cliffe IA, Dover GM, Forster EA, Haskins JT, Jones D, Mansell HL, Reilly Y. Eur J Pharmacol. 1993 Jun 24;237(2-3):283-91.

Silent 5-HT1A receptor antagonists: utility as research tools and therapeutic - Silent 5-HT1A receptor antagonists: utility as research tools and therapeutic

Fletcher A, Cliffe IA, Dourish CT. Trends Pharmacol Sci. 1993 Dec;14(12):41-8.

Anxiolytic-like effect of (S)-WAY 100135, a 5-HT1A receptor antagonist, in the - Anxiolytic-like effect of (S)-WAY 100135, a 5-HT1A receptor antagonist, in the

Rodgers RJ, Cole JC. Eur J Pharmacol. 1994 Aug 22;261(3):321-5.