WAY 161503 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4380
• Prices: $139.00, $579.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 276695-22-8
• Chemical Name: 8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-onehydrochloride
• Formula: C11H11Cl2N3O.HCl
• Molecular Weight: 308.59
• Purity: >99 %
• Description: Potent and selective 5-HT 2C receptor agonist (K i = 4 nM; EC 50 = 12 nM). Antidepressant following systemic administration in vivo .

Product References

Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) - Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C)

Cryan JF, Lucki I. J Pharmacol Exp Ther. 2000 Dec;295(3):1120-6.

Synthesis and 5-hydroxytryptamine (5-HT) activity of - Synthesis and 5-hydroxytryptamine (5-HT) activity of

Welmaker GS, Nelson JA, Sabalski JE, Sabb AL, Potoski JR, Graziano D, Kagan M, Coupet J, Dunlop J, Mazandarani H, Rosenzweig-Lipson S, Sukoff S, Zhang Y. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1991-4.

Design, synthesis, and pharmacological characterization of N- and O-substituted - Design, synthesis, and pharmacological characterization of N- and O-substituted

Jensen AA, Plath N, Pedersen MH, Isberg V, Krall J, Wellendorph P, Stensbol TB, Gloriam DE, Krogsgaard-Larsen P, Frolund B. J Med Chem. 2013 Feb 14;56(3):1211-27.