WAY 200070

• Supplier: Tocris Bioscience
• Catalog: 5589
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 440122-66-7
• Chemical Name: 7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol
• Formula: C13H8BrNO3
• Molecular Weight: 306.11
• Purity: >98 %
• Description: Selective ER β receptor agonist that displays 68-fold selectivity over ER α (EC 50 values are 2 and 155 nM for ER β and ER α respectively). Displays antianxiolytic and antidepressive effects in vivo .

Product References

Design and synthesis of aryl diphenolic azoles as potent and selective estrogen - Design and synthesis of aryl diphenolic azoles as potent and selective estrogen

Malamas MS, Manas ES, McDevitt RE, Gunawan I, Xu ZB, Collini MD, Miller CP, Dinh T, Henderson RA, Keith JC Jr, Harris HA. J Med Chem. 2004 Oct 7;47(21):5021-40.

Differential effects of estrogen receptor alpha and beta specific agonists on - Differential effects of estrogen receptor alpha and beta specific agonists on

Clipperton AE, Spinato JM, Chernets C, Pfaff DW, Choleris E. Neuropsychopharmacology. 2008 Sep;33(10):2362-75. Epub 2007 Nov 14.

WAY-200070, a selective agonist of estrogen receptor beta as a potential novel - WAY-200070, a selective agonist of estrogen receptor beta as a potential novel

Hughes ZA, Liu F, Platt BJ, Dwyer JM, Pulicicchio CM, Zhang G, Schechter LE, Rosenzweig-Lipson S, Day M. Neuropharmacology. 2008 Jun;54(7):1136-42.