WAY 213613

• Supplier: Tocris Bioscience
• Catalog: 3904
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 868359-05-1
• Chemical Name: N-[4-(2-Bromo-4,5-difluorophenoxy)phenyl]-L-asparagine
• Formula: C16H13BrF2N2O4
• Molecular Weight: 415.19
• Purity: >99 %
• Description: Potent, non-substrate inhibitor of EAAT2 (GLT-1) that displays > 44-fold selectivity over EAAT1 and EAAT3 (IC 50 values are 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1 respectively). Exhibits no activity towards ionotropic and metabotropic glutamate receptors.

Product References

Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and - Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and

Dunlop J, McIlvain HB, Carrick TA, Jow B, Lu Q, Kowal D, Lin S, Greenfield A, Grosanu C, Fan K, Petroski R, Williams J, Foster A, Butera J. Mol Pharmacol. 2005 Oct;68(4):974-82. Epub 2005 Jul 13.

Transporters for L-glutamate: an update on their molecular pharmacology and - Transporters for L-glutamate: an update on their molecular pharmacology and

Beart PM, O'Shea RD. Br J Pharmacol. 2007 Jan;150(1):5-17. Epub 2006 Nov 6.