| Name | WH-4-023 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2339 |
| Prices | $235.00, $965.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 837422-57-8 |
| Chemical Name | 2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate |
| Formula | C32H36N6O4 |
| Molecular Weight | 568.67 |
| Purity | >98 % |
| Description | Potent and selective Lck and Src inhibitor (IC 50 values are 2 and 6 nM respectively). Exhibits >300-fold selectivity against p38 α and KDR. Also potently inhibits SIK (IC 50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases. Supports self-renewal of naive hESCs in combination with PD 0325901 , CHIR 99021 and SB 590885 . |
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