WIN 55,212-2 mesylate

• Supplier: Tocris Bioscience
• Catalog: 4736
• Prices: $89.00, $375.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 131543-23-2
• Chemical Name: (R)-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanonemesylate
• Formula: C27H26N2O3.CH3SO3H
• Molecular Weight: 522.61
• Purity: >98 %
• Description: Nanomolar affinity cannabinoid receptor agonist (K i values are 62.3 and 3.3 nM at the human cloned CB 1 and CB 2 receptors respectively). S-enantiomer WIN 55,212-3 mesylate (Cat. No. 2327) also available.

Product References

Conformationally restrained analogues of pravadoline: nanomolar potent, - Conformationally restrained analogues of pravadoline: nanomolar potent,

D'Ambra TE, Estep KG, Bell MR, Eissenstat MA, Josef KA, Ward SJ, Haycock DA, Baizman ER, Casiano FM, Beglin NC, et al.. J Med Chem. 1992 Jan;35(1):124-35.

Comparison of the pharmacology and signal transduction of the human cannabinoid - Comparison of the pharmacology and signal transduction of the human cannabinoid

Felder CC, Joyce KE, Briley EM, Mansouri J, Mackie K, Blond O, Lai Y, Ma AL, Mitchell RL. Mol Pharmacol. 1995 Sep;48(3):443-50.

Evaluation of cannabinoid receptor agonists and antagonists using the - Evaluation of cannabinoid receptor agonists and antagonists using the

Griffin G, Atkinson PJ, Showalter VM, Martin BR, Abood ME. J Pharmacol Exp Ther. 1998 May;285(2):553-60.

Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in - Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in

Martellotta MC, Cossu G, Fattore L, Gessa GL, Fratta W. Neuroscience. 1998 Jul;85(2):327-30.