| Name | WIN 55,212-3 mesylate |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1038 |
| Prices | $129.00, $535.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 131543-25-4 |
| Chemical Name | [(3S)-2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanonemonomethanesulfonate |
| Formula | C27H26N2O3.CH3SO3H |
| Molecular Weight | 522.61 |
| Purity | >98 % |
| Description | Novel, low potency CB 2 receptor silent antagonist and CB 1 receptor partial inverse agonist. Competitively antagonizes effects of CP 55,940 (pA 2 = 6.1) and SR 144528 (pEC 50 = 5.3) at CB 2 receptors and acts as a partial inverse agonist at CB 1 receptors (pIC 50 = 5.5). Displays modest activity at human melatonin MT 1 and muscarinic M 4 receptors, but is selective over several other GPCRs. |
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