WKYMVm

Name WKYMVm
Supplier Tocris Bioscience
Catalog 1799
Prices $139.00
Sizes 1 mg
Function Type Agonist
Cas Number 187986-17-0
Formula C41H61N9O7S2
Molecular Weight 856.11
Description Selective agonist for the formyl peptide receptors FPR1, FPR2 (EC 50 = 75 pM) and FPR3 (EC 50 = 3 nM), expressed on immune cells. Induces Ca 2+ mobilization and superoxide production in, and chemotaxic migration of, monocytes and neutrophils. Also promotes monocyte survival through a PKC-, PI 3-kinase- and Akt-dependent pathway.
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Product References

Utilization of two seven-transmembrane, G protein-coupled receptors, formyl - Utilization of two seven-transmembrane, G protein-coupled receptors, formyl

Le Y, Gong W, Li B, Dunlop NM, Shen W, Su SB, Ye RD, Wang JM. J Immunol. 1999 Dec 15;163(12):6777-84.

The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates - The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates

Christophe T, Karlsson A, Dugave C, Rabiet MJ, Boulay F, Dahlgren C. J Biol Chem. 2001 Jun 15;276(24):21585-93. Epub 2001 Apr 2.

The synthetic chemoattractant peptide, Trp-Lys-Tyr-Met-Val-D-Met, enhances - The synthetic chemoattractant peptide, Trp-Lys-Tyr-Met-Val-D-Met, enhances

Bae YS, Kim Y, Park JC, Suh PG, Ryu SH. J Leukoc Biol. 2002 Feb;71(2):329-38.