| Name | XAP 044 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4120 |
| Prices | $185.00, $755.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 196928-50-4 |
| Chemical Name | 7-Hydroxy-3-(4-iodophenoxy)-4H-1-benzopyran-4-one |
| Formula | C15H9IO4 |
| Molecular Weight | 380.13 |
| Purity | >98 % |
| Description | Potent and selective mGlu 7 antagonist (IC 50 = 88 nM); inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice. Displays no effects on the LTP of mGlu 7 deficient mice. Exhibits novel activity by binding to the mGlu 7 Venus flytrap domain (VFTD). Exhibits anti-anxiety effects in rodent models. Brain penetrant. |
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