| Name | XCT 790 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4220 |
| Prices | $169.00, $705.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 725247-18-7 |
| Chemical Name | 3-[4-(2,4-Bis-trifluoromethylbenzyloxy)-3-methoxyphenyl]-2-cyano-N-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)acrylamide |
| Formula | C23H13F9N4O3S |
| Molecular Weight | 596.42 |
| Purity | >99 % |
| Description | Selective ERR α antagonist/inverse agonist (IC 50 = ~400 nM). Displays no antagonist activity at ERR γ or ER α at concentrations below 10 μ M. Interferes with PPAR γ coactivator-1 α (PGC-1 α )/ERR α -dependent signaling: inhibits PGC-1 α induction of ERR α and MAO-B gene expression and downregulates the constitutive transcriptional activity of ERR α in numerous cell lines. |
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