XD 14

• Supplier: Tocris Bioscience
• Catalog: 3928
• Prices: $209.00, $879.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 1370888-71-3
• Chemical Name: 4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
• Formula: C20H27N3O5S
• Molecular Weight: 421.51
• Purity: >98 %
• Description: BET bromodomain inhibitor (K d values are 160, 170, 380, 490, 830 and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2) respectively). Also inhibits BRDT(1), CBP, p300 and BRDT(2) (K d values are 1.2, 1.6, 2.6 and 3.7 μ M respectively). Attenuates proliferation of HL-60 leukemia cells in vitro .