| Name | XL 388 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5422 |
| Prices | $235.00, $965.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1251156-08-7 |
| Chemical Name | [7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone |
| Formula | C23H22FN3O4S |
| Molecular Weight | 455.5 |
| Purity | >98 % |
| Description | Potent and selective mTOR inhibitor (IC 50 = 9.9 nM). Inhibits mTOR activity in an ATP-competitive manner. Exhibits >300-fold selectivity for mTOR over PI 3-K and a range of other kinases. Displays antitumor activity in athymic nude mice implanted with tumor xenografts. |
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