Y-25130 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2676
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 123040-16-4
• Chemical Name: N-(1-Azabicyclo[2.2.2]oct-3-yl)-6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxamidehydrochloride
• Formula: C17H20ClN3O3.HCl
• Molecular Weight: 386.28
• Purity: >99 %
• Description: A selective and potent 5-HT 3 antagonist (K i = 2.9 nM).

Product References

The antiemetic profile of Y-25130, a new selective 5-HT3 receptor antagonist. - The antiemetic profile of Y-25130, a new selective 5-HT3 receptor antagonist.

Fukuda T, Setoguchi M, Inaba K, Shoji H, Tahara T. Eur J Pharmacol. 1991 Apr 24;196(3):299-305.

Antagonistic activity of Y-25130 on 5-HT3 receptors. - Antagonistic activity of Y-25130 on 5-HT3 receptors.

Sato N, Sakamori M, Haga K, Takehara S, Setoguchi M. Jpn J Pharmacol. 1992 Aug;59(4):443-8.

The effects of orally administered Y-25130, a selective serotonin3-receptor - The effects of orally administered Y-25130, a selective serotonin3-receptor

Haga K, Inaba K, Shoji H, Morimoto Y, Fukuda T, Setoguchi M. Jpn J Pharmacol. 1993 Nov;63(3):377-83.