ZAPA sulfate

• Supplier: Tocris Bioscience
• Catalog: 2579
• Prices: $125.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 371962-01-5
• Chemical Name: (Z)-3-[(Aminoiminomethyl)thio]prop-2-enoicacidsulfate
• Formula: C4H6N2O2S.H2SO4
• Molecular Weight: 244.24
• Description: More potent than either GABA or muscimol as an agonist at low affinity GABA A receptors and is thus a useful ligand to investigate GABA receptors linked to benzodiazepine receptors. Also a GABA A - ρ receptor antagonist.

Product References

Isothiouronium compounds as gamma-aminobutyric acid agonists. - Isothiouronium compounds as gamma-aminobutyric acid agonists.

Allan RD, Dickenson HW, Hiern BP, Johnston GA, Kazlauskas R. Br J Pharmacol. 1986 Jun;88(2):379-87.

ZAPA, (Z)-3-[(aminoiminomethyl)thio]-2-propenoic acid hydrochloride, a potent - ZAPA, (Z)-3-[(aminoiminomethyl)thio]-2-propenoic acid hydrochloride, a potent

Holden-Dye L, Walker RJ. Br J Pharmacol. 1988 Sep;95(1):3-5.

GABAc receptors: relatively simple transmitter -gated ion channels? - GABAc receptors: relatively simple transmitter -gated ion channels?

Johnston GA. Trends Pharmacol Sci. 1996 Sep;17(9):319-23.