Zardaverine

• Supplier: Tocris Bioscience
• Catalog: 0947
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 101975-10-4
• Chemical Name: 6-[4-(Difluoromethoxy)-3-methoxyphenyl]-3(2H)-pyridazinone
• Formula: C12H10F2N2O3
• Molecular Weight: 268.22
• Purity: >98 %
• Description: Phosphodiesterase inhibitor, selective for PDE3 and 4 (IC 50 values are 0.5 and 0.8 μ M respectively). Also available as part of the Phosphodiesterase Inhibitor Tocriset™ .

Product References

Is phosphodiesterase inhibition a relevant bronchospasmolytic principle? - Is phosphodiesterase inhibition a relevant bronchospasmolytic principle?

Kilian U, Beume R, Eltze M, Schudt C. Agents Actions Suppl. 1989;28:331-48.

Actions of the phosphodiesterase inhibitor zardaverine on guinea-pig ventricular - Actions of the phosphodiesterase inhibitor zardaverine on guinea-pig ventricular

Galvan M, Schudt C. Naunyn Schmiedebergs Arch Pharmacol. 1990 Aug;342(2):221-7.