ZD 9379

• Supplier: Tocris Bioscience
• Catalog: 1000
• Prices: $189.00
• Sizes: 10 mg
• Function Type: Antagonist
• Cas Number: 170142-20-8
• Chemical Name: 7-Chloro-2,3-dihydro-2-(4-methoxy-2-methylphenyl)pyridazino[4,5-b]quinoline-1,4,10(5H)trione
• Formula: C19H14ClN3O4
• Molecular Weight: 383.79
• Purity: >98 %
• Description: NMDA receptor antagonist; acts at glycine site. Neuroprotective; reduces infarct size and frequency of spreading depressions in a rat model of ischemic stroke. Brain penetrant.

Product References

Glycine site antagonist attenuates infarct size in experimental focal ischemia. - Glycine site antagonist attenuates infarct size in experimental focal ischemia.

Takano K, Tatlisumak T, Formato JE, Carano RA, Bergmann AG, Pullan LM, Bare TM, Sotak CH, Fisher M. Stroke. 1997 Jun;28(6):1255-62; discussion 1263.

A glycine site antagonist ZD9379 reduces number of spreading depressions and - A glycine site antagonist ZD9379 reduces number of spreading depressions and

Tatlisumak T, Takano K, Meiler MR, Fisher M. Acta Neurochir Suppl. 2000;76:331-3.