ZK 164015

• Supplier: Tocris Bioscience
• Catalog: 2675
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 177583-70-9
• Chemical Name: 2-(4-Hydroxyphenyl)-3-methyl-1-[10-(pentylsulfonyl)decyl]-1H-indol-5-ol
• Formula: C30H43NO4S
• Molecular Weight: 513.73
• Purity: >99 %
• Description: Potent estrogen receptor silent antagonist. Inhibits 17 β -estradiol stimulation of luciferase activity (IC 50 = 0.025 μ M); potently inhibits the growth of estrogen-sensitive human MCF-7 breast cancer cells in vitro (IC 50 ~ 1 nM).

Product References

The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast - The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast

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Synthesis and biological evaluation of stilbene-based pure estrogen antagonists. - Synthesis and biological evaluation of stilbene-based pure estrogen antagonists.

Walter G, Liebl R, von Angerer E. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4659-63.