| Name | ZK 756326 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2345 |
| Prices | $149.00, $629.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 874911-96-3 |
| Chemical Name | 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanoldihydrochloride |
| Formula | C21H28N2O3.2HCl |
| Molecular Weight | 429.38 |
| Purity | >99 % |
| Description | Selective, non-peptide CCR8 chemokine receptor agonist (IC 50 values are 1.8 and 2.6 μ M for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α 2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion. |
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