ZM 241385

Name ZM 241385
Supplier Tocris Bioscience
Catalog 0882
Prices $159.00, $665.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 139180-30-6
Chemical Name 4-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol
Formula C16H15N7O2
Molecular Weight 337.34
Purity >99 %
Description Potent and highly selective A 2A adenosine antagonist, with a pA 2 of 9.02 for A 2A receptors in guinea pig cardiac vasculature and selectivities of 1000, 91 and 500,000 over A 1 , A 2B and A 3 sites respectively. Active in vivo .
Supplier Page Shop

Product References

The in vitro pharmacology of ZM 241385, a potent, non-xanthine A2a selective - The in vitro pharmacology of ZM 241385, a potent, non-xanthine A2a selective

Poucher SM, Keddie JR, Singh P, Stoggall SM, Caulkett PW, Jones G, Coll MG. Br J Pharmacol. 1995 Jul;115(6):1096-102.

In vivo characterisation of ZM 241385, a selective adenosine A2A receptor - In vivo characterisation of ZM 241385, a selective adenosine A2A receptor

Keddie JR, Poucher SM, Shaw GR, Brooks R, Collis MG. Eur J Pharmacol. 1996 Apr 22;301(1-3):107-13.

Pharmacodynamics of ZM 241385, a potent A2a adenosine receptor antagonist, after - Pharmacodynamics of ZM 241385, a potent A2a adenosine receptor antagonist, after

Poucher SM, Keddie JR, Brooks R, Shaw GR, McKillop D. J Pharm Pharmacol. 1996 Jun;48(6):601-6.