| Name | ZM 39923 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1321 |
| Prices | $175.00, $709.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 58753-54-1 |
| Chemical Name | 3-benzylisopropylamino-1-naphthalen-2-yl-propan-1-onehydrochloride |
| Formula | C23H25NO.HCl |
| Molecular Weight | 367.92 |
| Purity | >99 % |
| Description | Potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3). pIC 50 values are 7.1, 5.6, 4.4, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively. Breaks down in neutral buffer (t ½ = 36 mins, pH 7.43, 25°C) to form ZM 449829 (Cat. No. 1366). |
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