Zoledronic Acid

Name Zoledronic Acid
Supplier Tocris Bioscience
Catalog 1070
Prices $69.00, $295.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 118072-93-8
Chemical Name [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonicacid
Formula C5H10N2O7P2
Molecular Weight 272.09
Purity >98 %
Description Potent bisphophonate farnesyl diphosphate (FPP) synthase inhibitor (IC 50 = 20 nM). Inhibits osteoclast-mediated bone resorption. Also inhibits Ras signaling and tumor growth, and induces apoptosis in pancreatic cancer cells. Reverses epithelial-mesenchymal transition and inhibits breast cancer cell renewal via inactivation of NF- κ B.
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