Zopiclone

• Supplier: Tocris Bioscience
• Catalog: 2625
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 43200-80-2
• Chemical Name: 4-Methyl-1-piperazinecarboxylicacid6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-ylester
• Formula: C17H17ClN6O3
• Molecular Weight: 388.81
• Purity: >99 %
• Description: A non benzodiazepine BZR agonist, with little difference in affinity for the BZ1 and BZ2 subtypes; however its CNS effects differ from those of other BZR ligands and this may be due to interaction with a different subunit.

Product References

Zopiclone. A review of its pharmacodynamic and pharmacokinetic properties and - Zopiclone. A review of its pharmacodynamic and pharmacokinetic properties and

Goa KL, Heel RC. Drugs. 1986 Jul;32(1):48-65.

Potentiation of gamma-aminobutyric acid-induced chloride currents by various - Potentiation of gamma-aminobutyric acid-induced chloride currents by various

Im HK, Im WB, Hamilton BJ, Carter DB, Vonvoigtlander PF. Mol Pharmacol. 1993 Oct;44(4):866-70.

Heterogeneous distribution of benzodiazepine receptors among rat neostriatal - Heterogeneous distribution of benzodiazepine receptors among rat neostriatal

Munakata M, Nakanishi R, Akaike N. Br J Pharmacol. 1996 Jun;118(3):820-5.