Lactacystin

Name Lactacystin
Supplier Boston Biochem
Catalog 2267
Prices $265.00
Sizes 200 µg
Function Type Inhibitor
Purity > 98% by HPLC. Structure confirmed by H-NMR.
Description Potent, highly specific, irreversible and cell-permeable inhibitor that covalently modifies the catalytic β subunits (chymotrypsin-, trypsin- and caspase-like activities) of the proteasome. Lactacystin is hydrolyzed in aqueous solutions to a clasto-lactacystin β-lactone intermediate which is the active inhibitory species that reacts with the proteasome.
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