Name | Lactacystin |
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Supplier | Boston Biochem |
Catalog | 2267 |
Prices | $265.00 |
Sizes | 200 µg |
Function Type | Inhibitor |
Purity | > 98% by HPLC. Structure confirmed by H-NMR. |
Description | Potent, highly specific, irreversible and cell-permeable inhibitor that covalently modifies the catalytic β subunits (chymotrypsin-, trypsin- and caspase-like activities) of the proteasome. Lactacystin is hydrolyzed in aqueous solutions to a clasto-lactacystin β-lactone intermediate which is the active inhibitory species that reacts with the proteasome. |
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