PS-341

• Supplier: Boston Biochem
• Catalog: I-200
• Prices: $189.00
• Sizes: 5 mg
• Function Type: Inhibitor
• Purity: >99% by HPLC and TLC
• Description: The dipeptide-boronic acid analogue PS-341 is the active ingredient in Bortezomib (Velcade, Millennium Pharmaceuticals). This potent, cell permeable molecule inhibits primarily the chymotryptic activity of the proteasome without substantially altering tryptic or caspase-like activities. PS-341 inhibits proliferation of a number of tumor cell lines with nanomolar potency, and is approved by the USFDA for the treatment of multiple myeloma.