MAP1LC3A-Rhodamine110

Name MAP1LC3A-Rhodamine110
Supplier Boston Biochem
Catalog UL-455
Prices $399.00
Sizes 50 µg
Function Type Inhibitor
Purity > 90% by SDS-PAGE
Description MAP1LC3A-Rhodamine110, human recombinant Microtubule-associated proteins 1A/1B light chain 3A (also known as MAP1LC3A) is an Ubiquitin-like modifier of the ATG8 family and is involved in the formation of the autophagosomes. This protein interacts directly with Sequestosome-1 and is recruited to inclusion bodies containing polyubiquitinated protein aggregates where it plays a role in inclusion body degradation by autophagy. MAP1LC3A-Rhodamine110 (Rh110) is a fluorogenic substrate for the autophagy hydrolase ATG4B. This substrate is useful for studying ATG4B when detection sensitivity or continuous monitoring of activity is essential.
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