Geldanamycin (HSP90 inhibitor)
| Name | Geldanamycin (HSP90 inhibitor) |
|---|---|
| Supplier | Boston Biochem |
| Catalog | I-605 |
| Prices | $110.00 |
| Sizes | 100 µg |
| Function Type | Inhibitor |
| Purity | >98% by HPLC |
| Description | Selectively inhibits heat shock protein 90 (HSP90). Binds to the ATP site of HSP90 (Kd = 1.2 µM) and inhibits its chaperone activity. Consequently inhibits activities of oncogenic kinases (e.g. src, Raf), p53 and steroid receptors. Demonstrates anti-proliferative effects on breast cancer cells in a dose dependent manner. |
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