Bosutinib, Free Base

Name Bosutinib, Free Base
Supplier Biorbyt
Catalog orb153604
Prices $238.00, $281.00, $340.00, $425.00, $570.00, $884.00, $1,420.00, $2,967.00
Sizes 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g, 2 g, 5 g
Cas Number [380843-75-4]
Pubchem 46926609
Chemical Name 4-(2,4-dichloro-5-methoxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-2-carbonitrile
Formula C26H29Cl2N5O3
Molecular Weight 530.45 g/mol
Purity >99% pure
Description Bosutinib is also named as SKI-606, is a novel tyrosine kinase inhibitor,It has a more potent than imatinib. Bosutinib can overcome by both Bcr-Abl-dependent and independent mechanisms. It is used to treat patients with chronic myelogenous leukemia (CML) who demonstrate resistance to imatinib or develop resistance during treatment. Bosutinib inhibits tumor cell proliferation, angiogenesis, growth factor expression and Src-mediated signaling pathways in vivo.
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