AS 2444697

• Supplier: R&D Systems
• Catalog: 5430
• Prices: $235.00, $965.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1287665-60-4
• Chemical Name: N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamidehydrochloride
• Formula: C19H20N6O4.HCl
• Molecular Weight: 432.86
• Purity: >98%

Product References

Recent advances in the discovery of small molecule inhibitors of interleukin-1 - Recent advances in the discovery of small molecule inhibitors of interleukin-1

Chaudhary D, Robinson S, Romero DL. J Med Chem. 2015 Jan 8;58(1):96-110.

Renoprotective effects of novel interleukin-1 receptor-associated kinase 4 - Renoprotective effects of novel interleukin-1 receptor-associated kinase 4

Kondo M, Tahara A, Hayashi K, Abe M, Inami H, Ishikawa T, Ito H, Tomura Y. Naunyn Schmiedebergs Arch Pharmacol. 2014 Oct;387(10):909-19. doi:

Blocking innate immunity to slow the progression of chronic kidney disease. - Blocking innate immunity to slow the progression of chronic kidney disease.

Schmaderer C, Heemann U. Naunyn Schmiedebergs Arch Pharmacol. 2014 Oct;387(10):905-7. doi: