HTMT dimaleate

• Supplier: Tocris Bioscience
• Catalog: 5622
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 195867-54-0
• Chemical Name: 6-[2-(4-Imidazolyl)ethylamino]-N-(4-trifluoromethylphenyl)heptanecarboxamidedimaleate
• Formula: C19H25F3N4O.2C4H4O4
• Molecular Weight: 614.57
• Purity: >99 %
• Description: H 1 and H 2 receptor agonist. 4x10 4 times more active than histamine in H 2 -mediated effects in natural suppressor cells. Increases intracellular Ca 2+ and IP 3 in lymphocytes through a binding site other than H 1 , H 2 or H 3 .

Product References

The effects of derivatives of histamine on natural suppressor cells. - The effects of derivatives of histamine on natural suppressor cells.

Khan MM, Marr-Leisy D, Verlander MS, Bristow MR, Strober S, Goodman M, Melmon KL. J Immunol. 1986 Jul 1;137(1):308-14.

Congener derivatives and conjugates of histamine: synthesis and tissue and - Congener derivatives and conjugates of histamine: synthesis and tissue and

Khan MM, Melmon KL, Marr-Leisy D, Verlander MS, Egli M, Lok S, Goodman M. J Med Chem. 1987 Nov;30(11):2115-20.