| Name | IQ 3 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5575 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 312538-03-7 |
| Chemical Name | 11H-Indeno[1,2-b]quinoxalin-11-oneO-(2-furanylcarbonyl)oxime |
| Formula | C20H11N3O3 |
| Molecular Weight | 341.32 |
| Purity | >98 % |
| Description | Selective JNK3 inhibitor (K d values are 66, 240 and 290 nM for JNK3, JNK1 and JNK2 respectively). Inhibits NF- κ B/AP1 transcriptional activity in THP1-Blue cells (IC 50 = 1.4 μ M). Also inhibits TNF- α and IL-6 production in vitro . |
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