KRCA 0008

Name KRCA 0008
Supplier Tocris Bioscience
Catalog 5475
Prices $219.00, $905.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1472795-20-2
Chemical Name 1,1'-[(5-Chloro-2,4-pyrimidinediyl)bis[imino(3-methoxy-4,1-phenylene)-4,1-piperazinediyl]]bisethanone
Formula C30H37ClN8O4
Molecular Weight 609.12
Purity >99 %
Description Potent Ack1 and anaplastic lymphoma kinase (ALK) dual inhibitor (IC 50 values are 4 and 12 nM respectively). Inhibits lung cancer H3122 cell proliferation (IC 50 = 80 nM). Attenuates H3122 cell xenograft tumor growth in mice. Orally bioavailable.
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