Liquiritigenin

• Supplier: Tocris Bioscience
• Catalog: 5552
• Prices: $205.00
• Sizes: 10 mg
• Function Type: Agonist
• Cas Number: 578-86-9
• Chemical Name: (S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• Formula: C15H12O4
• Molecular Weight: 256.25
• Purity: >98 %
• Description: Potent ER β agonist isolated from licorice root (EC 50 = 36.5 nM for activation of the ERE tk-Luc reporter by ER β in transfected U2OS cells). Displays 20-fold selectivity for ER β ; does not activate other nuclear receptors, including the androgen and glucocorticoid receptors. Displays anti-inflammatory effects.

Product References

Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of - Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of

Kim YW, Zhao RJ, Park SJ, Lee JR, Cho IJ, Yang CH, Kim SG, Kim SC. Br J Pharmacol. 2008 May;154(1):165-73.

Liquiritigenin is a plant-derived highly selective estrogen receptor beta - Liquiritigenin is a plant-derived highly selective estrogen receptor beta

Mersereau JE, Levy N, Staub RE, Baggett S, Zogovic T, Chow S, Ricke WA, Tagliaferri M, Cohen I, Bjeldanes LF, Leitman DC. Mol Cell Endocrinol. 2008 Feb 13;283(1-2):49-57.