MMF

• Supplier: Tocris Bioscience
• Catalog: 5683
• Prices: $49.00
• Sizes: 50 mg
• Function Type: Activator
• Cas Number: 2756-87-8
• Chemical Name: 2(E)-Butenedioicacid1-methylester
• Formula: C5H6O4
• Molecular Weight: 130.1
• Purity: >99 %
• Description: Nuclear factor (erythroid-derived-2)-like 2 (Nrf2) pathway activator. Also exhibits agonist activity at GPR109A. Primary metabolite of DMF (Cat. No. 4512).

Product References

Antihepatotoxic activity of monomethyl fumarate isolated from Fumaria indica. - Antihepatotoxic activity of monomethyl fumarate isolated from Fumaria indica.

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The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor - The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor

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Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A - Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A

Hanson J, Gille A, Zwykiel S, Lukasova M, Clausen BE, Ahmed K, Tunaru S, Wirth A, Offermanns S. J Clin Invest. 2010 Aug;120(8):2910-9.

Fumarates promote cytoprotection of central nervous system cells against - Fumarates promote cytoprotection of central nervous system cells against

Scannevin RH, Chollate S, Jung MY, Shackett M, Patel H, Bista P, Zeng W, Ryan S, Yamamoto M, Lukashev M, Rhodes KJ. J Pharmacol Exp Ther. 2012 Apr;341(1):274-84.