Name | 1-Naphthyl PP1 |
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Supplier | Tocris Bioscience |
Catalog | 5522 |
Prices | $255.00, $1,045.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 221243-82-9 |
Chemical Name | 1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Formula | C19H19N5 |
Molecular Weight | 317.39 |
Purity | >99 % |
Description | Selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl. (IC 50 values are 1.0, 0.6, 0.6, 18 and 22 μ M for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). Preferentially inhibits mutant over wild-type kinases (IC 50 values are 1.5 vs 1000 nM for I338G v-src and v-src respectively). |
Supplier Page | Shop |