| Name | NIBR 189 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5546 |
| Prices | $169.00, $705.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 1599432-08-2 |
| Chemical Name | (2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one |
| Formula | C21H21BrN2O3 |
| Molecular Weight | 429.31 |
| Purity | >99 % |
| Description | Potent and selective EBI2 (GPR183) receptor antagonist (IC 50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively). Exhibits selectivity for EBI2 over a panel of other receptors, enzymes and transporters. Blocks oxysterol-induced migration of U937 monocyte cells. Orally bioavailable. |
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