| Name | OSU 6162 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5682 |
| Prices | $159.00, $665.00 |
| Sizes | 10 mg, 50 mg |
| Cas Number | 156907-84-5 |
| Chemical Name | (3S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidinehydrochloride |
| Formula | C15H23NO2S.HCl |
| Molecular Weight | 317.87 |
| Purity | >98 % |
| Description | Dopamine stabilizer; lacks high affinity for various neuroreceptors in vitro (K i values are 447 and 1305 nM for D 2 and D 3 receptors respectively and > 1 μ M for other targets). Exhibits high D 2 receptor occupancy in vivo ; highly active on dopamine synthesis and turnover. Induces stabilizing effects on psychomotor function in behavioral tests without inducing hypolocomotion or catalepsy. |
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Nichols NF, Cimini MG, Haas JV, Staton BA, Tedroff J, Svensson KA. Neuropharmacology. 2002 Oct;43(5):817-24.
Natesan S, Svensson KA, Reckless GE, Nobrega JN, Barlow KB, Johansson AM, Kapur S. J Pharmacol Exp Ther. 2006 Aug;318(2):810-8. Epub 2006 Apr 28.