Peroxy Orange 1

• Supplier: Tocris Bioscience
• Catalog: 5549
• Prices: $225.00
• Sizes: 10 mg
• Cas Number: 1199576-10-7
• Chemical Name: 2',3',6',7'-Tetrahydro-12'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-spiro[isobenzofuran-1(3H),9'-[1H,5H,9H]xantheno[2,3,4-ij]quinolizin]-3-one
• Formula: C32H32BNO5
• Molecular Weight: 521.41
• Description: Fluorescent probe for imaging hydrogen peroxide (H 2 O 2 ); cell permeable. Displays an orange intracellular fluorescence in response to H 2 O 2 signals produced in RAW 264.7 macrophages and A431 cells during immune response and growth factor stimulation, respectively. Excitation wavelength 543 nm, emission between 545 and 750 nm.

Product References

A palette of fluorescent probes with varying emission colors for imaging hydrogen - A palette of fluorescent probes with varying emission colors for imaging hydrogen

Dickinson BC, Huynh C, Chang CJ. J Am Chem Soc. 2010 Apr 28;132(16):5906-15.

Chemistry and biology of reactive oxygen species in signaling or stress - Chemistry and biology of reactive oxygen species in signaling or stress

Dickinson BC, Chang CJ. Nat Chem Biol. 2011 Jul 18;7(8):504-11.

H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic - H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic

Woolley JF, Naughton R, Stanicka J, Gough DR, Bhatt L, Dickinson BC, Chang CJ, Cotter TG. PLoS One. 2012;7(7):e34050.