| Name | PF 06465469 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5640 |
| Prices | $265.00, $1,085.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1407966-77-1 |
| Chemical Name | (R)-3-(1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(3-methyl-4-(1-methylethyl))benzamide |
| Formula | C30H33N7O2 |
| Molecular Weight | 523.63 |
| Purity | >95 % |
| Description | Potent inhibitor of interleukin-2 inducible T cell kinase (ITK) (IC 50 = 2 nM). Also exhibits inhibitory activity against Bruton's tyrosine kinase (BTK) (IC 50 = 2 nM). Displays nanomolar potencies in a cell-based IP1 assay and human whole blood assay (IC 50 values are 31 and 48 nM respectively). |
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