| Name | VU 0357017 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5563 |
| Prices | $175.00, $709.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Modulator |
| Cas Number | 1135242-13-5 |
| Chemical Name | 4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylicacidethylesterhydrochloride |
| Formula | C18H27N3O3.HCl |
| Molecular Weight | 369.89 |
| Purity | >98 % |
| Description | Positive allosteric modulator of muscarinic M 1 receptors (EC 50 = 198 nM). Displays no activity at M 2 -M 5 at concentrations up to 30 μ M. Potentiates NMDA receptor currents in hippocampal neurons; activity reverses cognitive decifits in a rodent model of hippocampal-dependent memory. CNS penetrant. |
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