VU 0409551

Name VU 0409551
Supplier Tocris Bioscience
Catalog 5322
Prices $179.00, $745.00
Sizes 10 mg, 50 mg
Function Type Modulator
Cas Number 1363281-27-9
Chemical Name [6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone
Formula C20H17FN2O3
Molecular Weight 352.36
Purity >98 %
Description Selective mGlu 5 positive allosteric modulator (EC 50 = 260 nM). Selective for mGlu 5 over other mGluR subtypes, as well as 66 other receptors and ion channels. Selectively potentiates mGlu 5 signaling via G α q . Exhibits wake-promoting, antipsychotic-like and cognition-enhancing effects in animal models. Brain penetrant and orally available.
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