1400W dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 5455
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 214358-33-5
• Chemical Name: N-[[3-(Aminomethyl)phenyl]methyl]-ethanimidamidedihydrochloride
• Formula: C10H15N3.2HCl
• Molecular Weight: 250.17
• Purity: >99 %
• Description: Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo .

Product References

1400W is a slow, tight binding, and highly selective inhibitor of inducible - 1400W is a slow, tight binding, and highly selective inhibitor of inducible

Garvey EP, Oplinger JA, Furfine ES, Kiff RJ, Laszlo F, Whittle BJ, Knowles RG. J Biol Chem. 1997 Feb 21;272(8):4959-63.

Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in - Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in

Thomsen LL, Scott JM, Topley P, Knowles RG, Keerie AJ, Frend AJ. Cancer Res. 1997 Aug 1;57(15):3300-4.

Selective inhibition of inducible nitric oxide synthase prevents ischaemic brain - Selective inhibition of inducible nitric oxide synthase prevents ischaemic brain

Parmentier S, Bohme GA, Lerouet D, Damour D, Stutzmann JM, Margaill I, Plotkine M. Br J Pharmacol. 1999 May;127(2):546-52.