KG 5

• Supplier: R&D Systems
• Catalog: 5260
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Cas Number: 877874-85-6
• Chemical Name: 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
• Formula: C20H16F3N7OS
• Molecular Weight: 459.45
• Purity: >98%

Product References

Disruption of angiogenesis and tumor growth with an orally active drug that - Disruption of angiogenesis and tumor growth with an orally active drug that

Murphy EA, Shields DJ, Stoletov K, Dneprovskaia E, McElroy M, Greenberg JI, Lindquist J, Acevedo LM, Anand S, Majeti BK, Tsigelny I, Saldanha A, Walsh B, Hoffman RM, Bouvet M, Klemke RL, Vogt PK, Arnold L, Wrasidlo W, Cheresh DA. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4299-304. doi:

A MEK-independent role for CRAF in mitosis and tumor progression. - A MEK-independent role for CRAF in mitosis and tumor progression.

Mielgo A, Seguin L, Huang M, Camargo MF, Anand S, Franovic A, Weis SM, Advani SJ, Murphy EA, Cheresh DA. Nat Med. 2011 Nov 13;17(12):1641-5.