| Name | CZC 24832 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5459 |
| Prices | $255.00, $1,045.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1159824-67-5 |
| Chemical Name | 5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-3-pyridinesulfonamide |
| Formula | C15H17FN6O2S |
| Molecular Weight | 364.4 |
| Purity | >98 % |
| Description | Selective inhibitor of PI 3-kinase γ (IC 50 = 1.0 μ M in a PI 3-K γ -dependent fMLP-induced neutrophil migration assay). Exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins. Orally effective in a rodent model of inflammatory disease. |
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