| Name | MI 2 dihydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5647 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Chemical Name | 4-[4-(4,5-Dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propylthieno[2,3-d]pyrimidinedihydrochloride |
| Formula | C18H25N5S2.2HCl |
| Molecular Weight | 448.48 |
| Purity | >98 % |
| Description | Menin-MLL interaction inhibitor; binds menin (IC 50 = 446 nM). Selectively inhibits proliferation and induces apoptosis of leukemia cells harboring MLL fusion proteins. Also blocks transformation and induces hematopoietic differentiation of MLL-AF9 transformed bone marrow cells. |
| Supplier Page | Shop |