| Name | MI 2 (MALT1 inhibitor) |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4707 |
| Prices | $225.00, $925.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1047953-91-2 |
| Chemical Name | 2-Chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenylacetamide |
| Formula | C19H17Cl3N4O3 |
| Molecular Weight | 455.72 |
| Purity | >98 % |
| Description | MALT1 inhibitor (IC 50 = 5.84 μ M). Binds directly to MALT1 and irreversibly suppresses protease function. Decreases NF- κ B activity induced by MALT1. Inhibits cell proliferation and MALT1-mediated cleavage activity. Suppresses human TMD8 and HBL-1 activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) tumor xenografts in mice and primary human ABC-DLBCLs ex vivo . |
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