Name | MSC 2032964A |
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Supplier | Tocris Bioscience |
Catalog | 5685 |
Prices | $189.00, $765.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 1124381-43-6 |
Chemical Name | N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide |
Formula | C16H13F3N6O |
Molecular Weight | 362.31 |
Purity | >98 % |
Description | Potent and selective ASK1 inhibitor (IC 50 = 93 nM). Selective for ASK1 over a panel of 210 kinases. Blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes. Suppresses neuroinflammation in a mouse EAE model. Orally bioavailable and brain penetrant. |
Supplier Page | Shop |